Ferrarelli F, Tononi G. Reduced sleep spindle activity point to a TRN-MD thalamus-PFC circuit dysfunction in schizophrenia. Schizophr Res. 2017;180:36–43.
Danos P, Schmidt A, Baumann B, Bernstein H-G, Northoff G, Stauch R, et al. Volume and neuron number of the mediodorsal thalamic nucleus in schizophrenia: a replication study. Psychiatry Res. 2005;140:281–9.
Byne W, Buchsbaum MS, Mattiace LA, Hazlett EA, Kemether E, Elhakem SL, et al. Postmortem assessment of thalamic nuclear volumes in subjects with schizophrenia. Am J Psychiatry. 2002;159:59–65.
Woodward ND, Heckers S. Mapping thalamocortical functional connectivity in chronic and early stages of psychotic disorders. Biol Psychiatry. 2016;79:1016–25.
Woodward ND, Karbasforoushan H, Heckers S. Thalamocortical dysconnectivity in schizophrenia. Am J Psychiatry. 2012;169:1092–9.
Anticevic A, Cole MW, Repovs G, Murray JD, Brumbaugh MS, Winkler AM, et al. Characterizing thalamo-cortical disturbances in schizophrenia and bipolar illness. Cereb Cortex. 2014;24:3116–30.
Marenco S, Stein JL, Savostyanova AA, Sambataro F, Tan H-Y, Goldman AL, et al. Investigation of anatomical thalamo-cortical connectivity and FMRI activation in schizophrenia. Neuropsychopharmacology. 2012;37:499–507.
Uhlhaas PJ, Roux F, Singer W. Thalamocortical synchronization and cognition: implications for schizophrenia? Neuron. 2013;77:997–9.
Article CAS PubMed Google Scholar
Eryilmaz H, Tanner AS, Ho NF, Nitenson AZ, Silverstein NJ, Petruzzi LJ, et al. Disrupted working memory circuitry in schizophrenia: disentangling fMRI markers of core pathology vs other aspects of impaired performance. Neuropsychopharmacology. 2016;41:2411–20.
Article CAS PubMed PubMed Central Google Scholar
Fernandez LM, Lüthi A. Sleep spindles: mechanisms and functions. Physiol Rev. 2020;100:805–68.
Kozhemiako N, Wang J, Jiang C, Wang LA, Gai G, Zou K, et al. Non-rapid eye movement sleep and wake neurophysiology in schizophrenia. Elife. 2022;11:e76211.
Article CAS PubMed PubMed Central Google Scholar
Ferrarelli F, Huber R, Peterson MJ, Massimini M, Murphy M, Riedner BA, et al. Reduced sleep spindle activity in schizophrenia patients. Am J Psychiatry. 2007;164:483–92.
Ferrarelli F, Peterson MJ, Sarasso S, Riedner BA, Murphy MJ, Benca RM, et al. Thalamic dysfunction in schizophrenia suggested by whole-night deficits in slow and fast spindles. Am J Psychiatry. 2010;167:1339–48.
Article PubMed PubMed Central Google Scholar
Bagautdinova J, Mayeli A, Wilson JD, Donati FL, Colacot RM, Meyer N, et al. Sleep abnormalities in different clinical stages of psychosis: a systematic review and meta-analysis. JAMA Psychiatry. 2023;80:202–10.
Article PubMed PubMed Central Google Scholar
Manoach DS, Demanuele C, Wamsley EJ, Vangel M, Montrose DM, Miewald J, et al. Sleep spindle deficits in antipsychotic-naïve early course schizophrenia and in non-psychotic first-degree relatives. Front Hum Neurosci. 2014;8:762.
Article PubMed PubMed Central Google Scholar
Buchmann A, Dentico D, Peterson MJ, Riedner BA, Sarasso S, Massimini M, et al. Reduced mediodorsal thalamic volume and prefrontal cortical spindle activity in schizophrenia. Neuroimage. 2014;102:540–7.
McCormick DA. Neurotransmitter actions in the thalamus and cerebral cortex. J Clin Neurophysiol. 1992;9:212–23.
Article CAS PubMed Google Scholar
Sanchez-Vives MV, Barbero-Castillo A, Perez-Zabalza M, Reig R. GABAB receptors: modulation of thalamocortical dynamics and synaptic plasticity. Neuroscience. 2021;456:131–42.
Article CAS PubMed Google Scholar
Just N, Sonnay S. Investigating the role of glutamate and GABA in the modulation of transthalamic activity: a combined fMRI-fMRS study. Front Physiol. 2017;8:30.
Article PubMed PubMed Central Google Scholar
Bartho P, Slezia A, Matyas F, Faradzs-Zade L, Ulbert I, Harris KD, et al. Ongoing network state controls the length of sleep spindles via inhibitory activity. Neuron. 2014;82:1367–79.
Article CAS PubMed PubMed Central Google Scholar
Krosigk von M, Bal T, McCormick DA. Cellular mechanisms of a synchronized oscillation in the thalamus. Science. 1993;261:361–4.
Lustenberger C, O’Gorman RL, Pugin F, Tüshaus L, Wehrle F, Achermann P, et al. Sleep spindles are related to schizotypal personality traits and thalamic glutamine/glutamate in healthy subjects. Schizophr Bull. 2015;41:522–31.
Kiemes A, Davies C, Kempton MJ, Lukow PB, Bennallick C, Stone JM, et al. GABA, glutamate and neural activity: a systematic review with meta-analysis of multimodal 1H-MRS-fMRI studies. Front Psychiatry. 2021;12:644315.
Article PubMed PubMed Central Google Scholar
Kraguljac NV, White DM, Reid MA, Lahti AC. Increased hippocampal glutamate and volumetric deficits in unmedicated patients with schizophrenia. JAMA Psychiatry. 2013;70:1294–302.
Article CAS PubMed PubMed Central Google Scholar
Kim S-Y, Kaufman MJ, Cohen BM, Jensen JE, Coyle JT, Du F, et al. In vivo brain glycine and glutamate concentrations in patients with first-episode psychosis measured by echo time–averaged proton magnetic resonance spectroscopy at 4T. Biol Psychiatry. 2018;83:484–91.
Article CAS PubMed Google Scholar
Birur B, Kraguljac NV, Shelton RC, Lahti AC. Brain structure, function, and neurochemistry in schizophrenia and bipolar disorder—a systematic review of the magnetic resonance neuroimaging literature. NPJ Schizophr. 2017;3:15.
Article PubMed PubMed Central Google Scholar
Merritt K, McGuire PK, Egerton A, Aleman A, Block W, Bloemen OJ, et al. Association of age, antipsychotic medication, and symptom severity in schizophrenia with proton magnetic resonance spectroscopy brain glutamate level: a mega-analysis of individual participant-level data. JAMA psychiatry. 2021;78:667–81.
Iwata Y, Nakajima S, Plitman E, Caravaggio F, Kim J, Shah P, et al. Glutamatergic neurometabolite levels in patients with ultra-treatment-resistant schizophrenia: a cross-sectional 3T proton magnetic resonance spectroscopy study. Biol Psychiatry. 2019;85:596–605.
Article CAS PubMed Google Scholar
Kaminski J, Gleich T, Fukuda Y, Katthagen T, Gallinat J, Heinz A, et al. Association of cortical glutamate and working memory activation in patients with schizophrenia: a multimodal proton magnetic resonance spectroscopy and functional magnetic resonance imaging study. Biol Psychiatry. 2020;87:225–33.
Article CAS PubMed Google Scholar
Kumar V, Vajawat B, Rao NP. Frontal GABA in schizophrenia: A meta-analysis of 1H-MRS studies. World J Biol Psychiatry. 2021;22:1–13.
Article CAS PubMed Google Scholar
Kegeles LS, Mao X, Stanford AD, Girgis R, Ojeil N, Xu X, et al. Elevated prefrontal cortex γ-aminobutyric acid and glutamate-glutamine levels in schizophrenia measured in vivo with proton magnetic resonance spectroscopy. Arch Gen Psychiatry. 2012;69:449–59.
Article CAS PubMed Google Scholar
Mayeli A, Sonnenschein SF, Yushmanov VE, Wilson JD, Blazer A, Foran W, et al. Dorsolateral prefrontal cortex glutamate/gamma-aminobutyric acid (GABA) alterations in clinical high risk and first-episode schizophrenia: a preliminary 7-T magnetic resonance spectroscopy imaging study. Int J Mol Sci. 2022;23:15846.
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