Mali, H., Shah, C., Raghunandan, B. H., Prajapati, A. S., Patel, D. H., Trivedi, U., & Subramanian, R. B. (2023). Organophosphate pesticides an emerging environmental contaminant: Pollution, toxicity, bioremediation progress, and remaining challenges. Journal of Environmental Sciences, 127, 234–250.

Article  CAS  Google Scholar 

Maxwell, D. M., Brecht, K. M., Koplovitz, I., & Sweeney, R. E. (2006). Acetylcholinesterase inhibition: does it explain the toxicity of organophosphorus compounds? Archives of Toxicology, 80, 756–760.

Article  CAS  PubMed  Google Scholar 

Karami-Mohajeri, S., & Abdollahi, M. (2013). Mitochondrial dysfunction and organophosphorus compounds. Toxicology and Applied Pharmacology, 270, 39–44.

Article  CAS  PubMed  Google Scholar 

Sharma, P., Sharma, A., Jasuja, N. D., & Joshi, S. C. (2014). Organophosphorous compounds and oxidative stress: a review. Toxicological & Environmental Chemistry, 96, 681–698.

Article  CAS  Google Scholar 

Tang, J., Zhang, M., Cheng, G., & Lu, Y. (2009). Diazinon determination using high performance liquid chromatography: a comparison of the ENVI-Carb column with the immunoaffinity column for the pretreatment of water and soil samples. Bulletin of Environmental Contamination and Toxicology, 83, 626–629.

Article  CAS  PubMed  Google Scholar 

Grafitt, S. J., Jones, K., Mason, H. J., & Cocker, J. (2002). Exposure to the organophosphate diazinon: data from a human volunteer study with oral and dermal doses. Toxicology Letters, 134, 105–113.

Article  Google Scholar 

Matsushita, T., Kikkawa, Y., Omori, K., Matsui, Y., & Shirasaki, N. (2021). Metabolism-Coupled Cell-Independent Acetylcholinesterase Activity Assay for Evaluation of the Effects of Chlorination on Diazinon Toxicity. Chemical Research in Toxicology, 34, 2070–2078.

Article  CAS  PubMed  Google Scholar 

Kappers, W. A., Edwards, R. J., Murray, S., & Boobis, A. R. (2001). Diazinon is activated by CYP2C19 in human liver. Toxicology and Applied Pharmacology, 177, 68–76.

Article  CAS  PubMed  Google Scholar 

Nassar, W. M., El-Kholy, W. M., El-Sawi, M. R., El-Shafai, N. M., Alotaibi, B. S., Ghamry, H. I., & Shukry, M. (2023). Ameliorative Effect of Thymoquinone and Thymoquinone Nanoparticles against Diazinon-Induced Hepatic Injury in Rats: A Possible Protection Mechanism. Toxics, 11, 783.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Saraei, F., Sadraie, S. H., Kaka, G. R., Sadoughi, M., Afzal Nejad, N., & Sarahian, N. (2023). Effects of maternal diazinon exposure on frontal cerebral cortical development in mouse embryo. International Journal of Neuroscience, 133, 152–158.

Article  CAS  PubMed  Google Scholar 

Elshafae, R., Elkomy, A., Farrag, E., Fadl, S., Soliman, A. G., & Aboubakr, M. (2023). Potential protective effects of ginger and atorvastatin against diazinon-induced hepatotoxicity in rats: A comparative histopathological, immunohistochemical, and biochemical study. Benha Veterinary Medical Journal, 44, 66–70.

Article  Google Scholar 

Dong, G., Li, Q., Yu, C., Wang, Q., Zuo, D., & Li, X. (2024). n-Acetylcysteine protects against diazinon-induced histopathological damage and apoptosis in renal tissue of rats. Toxicological Research, 40, 285–295.

Article  CAS  PubMed  Google Scholar 

Al-Attar, A. M., Elnaggar, M. H., & Almalki, E. A. (2017). Protective effect of some plant oils on diazinon induced hepatorenal toxicity in male rats. Saudi Journal of Biological Sciences, 24, 1162–1171.

Article  CAS  PubMed  Google Scholar 

Madhusudhan, B. (2009). Potential benefits of flaxseed in health and disease – a perspective. Agriculturae Conspectus Scientificus, 74, 67–72.

Google Scholar 

Bekhit, A. E., Shavandi, A., Jodjaja, T., Birch, J., Teh, S., Ahmed, I. A., Al-Juhaimi, F. Y., Saeedi, P., & Bekhit, A. A. (2018). Flaxseed: Composition, detoxification, utilization, and opportunities. Biocatalysis and Agricultural Biotechnology, 13, 129–152.

Article  Google Scholar 

Kasote, D. M. Flaxseed phenolics as natural antioxidants. International Food Research Journal. 2013;20.

Salem, M. O., Taştan, Y., Bilen, S., Terzi, E., & Sönmez, A. Y. (2023). Dietary flaxseed (Linum usitatissimum) oil supplementation affects growth, oxidative stress, immune response, and diseases resistance in rainbow trout (Oncorhynchus mykiss). Fish and Shellfish Immunology, 138, 108798.

Article  CAS  PubMed  Google Scholar 

Mehri, F., Ranjbar, A., Shirafkan, N., Asl, S. S., & Esfahani, M. (2022). The protective effect of resveratrol on diazinon‐induced oxidative stress and glucose hemostasis disorder in rats’ liver. Journal of Biochemical and Molecular Toxicology, 36(7), e23063.

Article  PubMed  Google Scholar 

Lotfi, S., Esfahani, M., Ranjbar, A., & Mehri, F. (2023). Protective effect of flaxseed oil the on diazinon-induced hepatotoxicity in male rats. Proceedings of the Indian National Science Academy, 89(3), 655–663.

Article  Google Scholar 

Makhdoomi, S., Fadaiie, A., Mohammadi, M., Ranjbar, A., & Haddadi, R. (2024). Quercetin’s Restorative Properties in Male Mice with 3-Nitropropionic Acid-induced Huntington-like Symptoms: Molecular Docking, Behavioral, and Biochemical Assessment. Cell Biochemistry and Biophysics, 82, 1489–1502.

Article  CAS  PubMed  Google Scholar 

Ivanović, S. R., Borozan, N., Miladinović, DĆ, Živković, I., & Borozan, S. The relationship between the cholinergic mechanism of toxicity and oxidative stress in rats during subacute diazinon poisoning. Toxicology and Applied Pharmacology. 2023 Jun:116598.

Esfahani, M., Rahbar, A. H., Soleimani Asl, S., & Mehri, F. (2023). Resveratrol: a panacea compound for diazinon-induced renal toxicity. Toxin Reviews, 42, 40–50.

Article  CAS  Google Scholar 

Georgiadis, G., Mavridis, C., Belantis, C., Zisis, I. E., Skamagkas, I., Fragkiadoulaki, I., Heretis, I., Tzortzis, V., Psathakis, K., Tsatsakis, A., & Mamoulakis, C. (2018). Nephrotoxicity issues of organophosphates. Toxicology, 406, 129–136.

Article  PubMed  Google Scholar 

Fath, E. M., Bakery, H. H., Shawarby, R. M., Abosalem, M. E., Ebrahim, N., Hegazy, A. M., & Ibrahim, S. S. (2023). Nephroprotective Effect of N-Acetyl-L-Cysteine against Diazinon-induced Nephrotoxicity in Rats via IKβ, NFκB, NLRP3 Signaling Pathway. Journal of Advanced Veterinary Research, 13, 1566–1574.

Google Scholar 

Naqshbandi, A., Rizwan, S., & Khan, F. (2013). Dietary supplementation of flaxseed oil ameliorates the effect of cisplatin on rat kidney. Journal of Functional Foods, 5, 316–326.

Article  CAS  Google Scholar 

Goyal, A., Sharma, V., Upadhyay, N., Gill, S., & Sihag, M. (2014). Flax and flaxseed oil: an ancient medicine & modern functional food. Journal of Food Science and Technology, 51, 1633–1653.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Omar, A. M. (2018). The potential protective influence of flaxseed oil against renal toxicity induced by thioacetamide in rats. Saudi Journal of Biological Sciences, 25, 1696–1702.

Article  Google Scholar 

Vahidirad, M., Arab-Nozari, M., Mohammadi, H., Zamani, E., & Shaki, F. (2018). Protective effect of captopril against diazinon induced nephrotoxicity and neurotoxicity via inhibition of ROS-NO pathway. Drug and Chemical Toxicology, 41, 287–293.

Article  CAS  PubMed  Google Scholar 

Ogasawara, N., Matsushima, M., Kawamura, N., Atsumi, K., Yamaguchi, T., Ochi, H., Kusatsugu, Y., Oyabu, S., Hashimoto, N., Hasegawa, Y., & Ueyama, J. (2017). Modulation of immunological activity on macrophages induced by diazinon. Toxicology, 379, 22–30.

Article  CAS  PubMed  Google Scholar 

Chali, S. E., Khanbabaei, R., Juybari, A. A., Fatahi, E., & Kalai, R. B. (2023). Coenzyme Q10 treatment and diazinon exposure in parental male rats: effects of the exposure on their neonatal brains. Toxicology Research, 12, 264–269.

Article  PubMed  PubMed Central  Google Scholar 

Banaee, M., Impellitteri, F., Multisanti, C. R., Sureda, A., Arfuso, F., Piccione, G., & Faggio, C. (2023). Evaluating Silymarin Extract as a Potent Antioxidant Supplement in Diazinon-Exposed Rainbow Trout: Oxidative Stress and Biochemical Parameter Analysis. Toxics, 11, 737.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Haddadi, R., Eyvari-Brooshghalan, S., Makhdoomi, S., Fadaiie, A., Komaki, A., & Daneshvar, A. (2024). Neuroprotective effects of silymarin in 3-nitropropionic acid-induced neurotoxicity in male mice: Improving behavioral deficits by attenuating oxidative stress and neuroinflammation. Naunyn-Schmiedeberg’s Archives of Pharmacology, 397, 2447–2463.

Article  CAS  PubMed  Google Scholar 

Rizwan, S., Naqshbandi, A., Farooqui, Z., Khan, A. A., & Khan, F. (2014). Protective effect of dietary flaxseed oil on arsenic-induced nephrotoxicity and oxidative damage in rat kidney. Food and Chemical Toxicology, 68, 99–107.

Article  CAS  PubMed  Google Scholar