This material is original research, has not been previously published and has not been submitted for publication elsewhere while under consideration. This work was partly supported by the National Maternity Hospital Foundation [grant number 210001]. The funder had no role in study design; collection, analysis nor interpretation of the data; writing of the report; nor in the decision to submit the manuscript for publication. No company involved in the manufacture, marketing, sale or distribution of any product in this study, or of any competing product, had any involvement in the study.