Dang CV, O’Donnell KA, Zeller KI, Nguyen T, Osthus RC, Li F. The c-Myc target gene network. Semin Cancer Biol. 2006;16:253–64.
ar-Rushdi A, Nishikura K, Erikson J, Watt R, Rovera G, Croce CM. Differential expression of the translocated and the untranslocated c-myc oncogene in Burkitt lymphoma. Science. 1983;222:390–3.
Dalla-Favera R, Bregni M, Erikson J, Patterson D, Gallo RC, Croce CM. Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. Proc Natl Acad Sci USA. 1982;79:7824–7.
Article PubMed PubMed Central Google Scholar
Taub R, Kirsch I, Morton C, Lenoir G, Swan D, Tronick S, et al. Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells. Proc Natl Acad Sci USA. 1982;79:7837–41.
Article PubMed PubMed Central Google Scholar
Rabbitts TH, Hamlyn PH, Baer R. Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma. Nature. 1983;306:760–5.
Pelengaris S, Khan M, Evan G. c-MYC: more than just a matter of life and death. Nat Rev Cancer. 2002;2:764–76.
Lee KS, Kwak Y, Nam KH, Kim DW, Kang SB, Choe G, et al. c-MYC copy-number gain is an independent prognostic factor in patients with colorectal cancer. PLoS One. 2015;10:e0139727.
Article PubMed PubMed Central Google Scholar
Kakisako K, Miyahara M, Uchino S, Adachi Y, Kitano S. Prognostic significance of c-myc mRNA expression assessed by semi-quantitative RT-PCR in patients with colorectal cancer. Oncol Rep. 1998;5:441–5.
Bhatavdekar JM, Patel DD, Ghosh N, Chikhlikar PR, Trivedi TI, Suthar TP, et al. Coexpression of Bcl-2, c-Myc, and p53 oncoproteins as prognostic discriminants in patients with colorectal carcinoma. Dis Colon Rectum. 1997;40:785–90.
Rowley S, Newbold KM, Gearty J, Keighley MR, Donovan IA, Neoptolemos JP. Comparison of deoxyribonucleic acid ploidy and nuclear expressed p62 c-myc oncogene in the prognosis of colorectal cancer. World J Surg. 1990;14:545–50. discussion 551
Wang C, Zhang J, Yin J, Gan Y, Xu S, Gu Y, et al. Alternative approaches to target Myc for cancer treatment. Sig Transduct Target Ther. 2021;6:1–14.
Struntz NB, Chen A, Deutzmann A, Wilson RM, Stefan E, Evans HL, et al. Stabilization of the max homodimer with a small molecule attenuates Myc-driven transcription. Cell Chem Biol. 2019;26:711–23.e14.
Llombart V, Mansour MR. Therapeutic targeting of “undruggable” MYC. EBioMedicine 2021;75:103756.
Article PubMed PubMed Central Google Scholar
Whitfield JR, Beaulieu ME, Soucek L. Strategies to inhibit Myc and their clinical applicability. Front Cell Dev Biol [Internet]. 2017;5. [cited 2024 Feb 17]. Available from: https://www.frontiersin.org/articles/10.3389/fcell.2017.00010
De Benedetti A, Graff JR. eIF-4E expression and its role in malignancies and metastases. Oncogene. 2004;23:3189–99.
Shi Y, Sharma A, Wu H, Lichtenstein A, Gera J. Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway*. J Biol Chem. 2005;280:10964–73.
Nanbru C, Lafon I, Audigier S, Gensac MC, Vagner S, Huez G, et al. Alternative translation of the proto-oncogene c-myc by an internal ribosome entry site. J Biol Chem. 1997;272:32061–6.
Stoneley M, Paulin FE, Quesne JPL, Chappell SA, Willis AE. C-Myc 5′ untranslated region contains an internal ribosome entry segment. Oncogene. 1998;16:423–8.
Walsh D, Mathews MB, Mohr I. Tinkering with translation: protein synthesis in virus-infected cells. Cold Spring Harb Perspect Biol. 2013;5:a012351.
Article PubMed PubMed Central Google Scholar
Pelletier J, Sonenberg N. Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature. 1988;334:320–5.
Jang SK, Kräusslich HG, Nicklin MJ, Duke GM, Palmenberg AC, Wimmer E. A segment of the 5’ nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. J Virol. 1988;62:2636–43.
Article PubMed PubMed Central Google Scholar
Komar AA, Hatzoglou M. Cellular IRES-mediated translation. Cell Cycle. 2011;10:229–40.
Article PubMed PubMed Central Google Scholar
Subkhankulova T, Mitchell SA, Willis AE. Internal ribosome entry segment-mediated initiation of c-Myc protein synthesis following genotoxic stress. Biochem J. 2001;359:183–92.
Article PubMed PubMed Central Google Scholar
Stoneley M, Chappell SA, Jopling CL, Dickens M, MacFarlane M, Willis AE. c-Myc protein synthesis is initiated from the internal ribosome entry segment during apoptosis. Mol Cell Biol. 2000;20:1162–9.
Article PubMed PubMed Central Google Scholar
Yeh DW, Zhao X, Siddique HR, Zheng M, Choi HY, Machida T, et al. MSI2 promotes translation of multiple IRES-containing oncogenes and virus to induce self-renewal of tumor initiating stem-like cells. Cell Death Discov. 2023;9:1–15.
Grentzmann G, Ingram JA, Kelly PJ, Gesteland RF, Atkins JF. A dual-luciferase reporter system for studying recoding signals. RNA. 1998;4:479–86.
PubMed PubMed Central Google Scholar
Kozak M. New Ways of Initiating Translation in Eukaryotes? Mol Cell Biol. 2001;21:1899–907.
Article PubMed PubMed Central Google Scholar
Hellen CUT, Sarnow P. Internal ribosome entry sites in eukaryotic mRNA molecules. Genes Dev. 2001;15:1593–612.
Bert AG, Grépin R, Vadas MA, Goodall GJ. Assessing IRES activity in the HIF-1α and other cellular 5′ UTRs. RNA. 2006;12:1074–83.
Article PubMed PubMed Central Google Scholar
Baranick BT, Lemp NA, Nagashima J, Hiraoka K, Kasahara N, Logg CR. Splicing mediates the activity of four putative cellular internal ribosome entry sites. Proc Natl Acad Sci USA. 2008;105:4733–8.
Article PubMed PubMed Central Google Scholar
Wang Z, Weaver M, Magnuson NS. Cryptic promoter activity in the DNA sequence corresponding to the pim-1 5’-UTR. Nucleic Acids Res. 2005;33:2248–58.
Article PubMed PubMed Central Google Scholar
Van Eden ME, Byrd MP, Sherrill KW, Lloyd RE. Demonstrating internal ribosome entry sites in eukaryotic mRNAs using stringent RNA test procedures. RNA. 2004;10:720–30.
Shi Y, Yang Y, Hoang B, Bardeleben C, Holmes B, Gera J, et al. Therapeutic potential of targeting IRES-dependent c-myc translation in multiple myeloma cells during ER stress. Oncogene. 2016;35:1015–24.
Denk S, Schmidt S, Schurr Y, Schwarz G, Schote F, Diefenbacher M, et al. CIP2A regulates MYC translation (via its 5′UTR) in colorectal cancer. Int J Colorectal Dis. 2021;36:911–8.
Martinez-Useros J, Garcia-Carbonero N, Li W, Fernandez-Aceñero MJ, Cristobal I, Rincon R, et al. UNR/CSDE1 expression is critical to maintain invasive phenotype of colorectal cancer through regulation of c-MYC and epithelial-to-mesenchymal transition. J Clin Med. 2019;8:560.
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