Ginsenoside Rb1 reduced ischemic stroke-induced apoptosis through endoplasmic reticulum stress-associated IRE1/TRAF2/JNK pathway

Agrawal M, Kumar V, Kashyap MP et al (2011) Ischemic insult induced apoptotic changes in PC12 cells: protection by trans resveratrol. Eur J Pharmacol 666(1–3):5–11. https://doi.org/10.1016/j.ejphar.2011.05.015

Article  CAS  PubMed  Google Scholar 

Anfinogenova ND, Quinn MT, Schepetkin IA et al (2020) Alarmins and c-Jun N-terminal kinase (JNK) signaling in neuroinflammation. Cells 9(11). https://doi.org/10.3390/cells9112350

Bai Y, He Z, Duan W et al (2022) Sodium formononetin-3’-sulphonate alleviates cerebral ischemia-reperfusion injury in rats via suppressing endoplasmic reticulum stress-mediated apoptosis. BMC Neurosci 23(1):74. https://doi.org/10.1186/s12868-022-00762-4

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen JH, Kuo HC, Lee KF et al (2015) Global proteomic analysis of brain ti-ssues in transient ischemia brain damage in rats. Int J Mol Sci 16(6):11873–11891. https://doi.org/10.3390/ijms160611873

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen Y, Chen Z, Cheng W et al (2022) The role of the GRP78/PERK/ATF4 pathway in the ability of Gua Lou Gui Zhi decoction to attenuate apoptosis by inhibiting endoplasmic reticulum stress after ischemia-reperfusion injury. Front Biosci (Landmark Ed) 27(10):296. https://doi.org/10.31083/j.fbl2710296

Article  CAS  PubMed  Google Scholar 

Cheng Z, Zhang M, Ling C et al (2019) Neuroprotective effects of ginsenosides against cerebral ischemia. Molecules 24(6). https://doi.org/10.3390/molecules24061102

Chien MY, Chuang CH, Chern CM et al (2016) Salvianolic acid A alleviates ischemic brain injury through the inhibition of inflammation and apoptosis and the promotion of neurogenesis in mice. Free Radic Biol Med 99:508–519. https://doi.org/10.1016/j.freeradbiomed.2016.09.006

Article  CAS  PubMed  Google Scholar 

Ding L, Gao Z, Wu S et al (2023) Ginsenoside compound-K attenuates OVX-induced osteoporosis via the suppression of RANKL-induced osteoclastogenesis and oxidative stress. Nat Prod Bioprospect 13(1):49. https://doi.org/10.1007/s13659-023-00405-z

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dong JY, Xia KJ, Liang W et al (2021) Ginsenoside Rb1 alleviates colitis in mice via activation of endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 signaling pathway. Acta Pharmacol Sin 42(9):1461–1471. https://doi.org/10.1038/s41401-020-00561-9

Article  CAS  PubMed  Google Scholar 

Fan HJ, Tan ZB, Wu YT et al (2020) The role of ginsenoside Rb1, a potential natural glutathione reductase agonist, in preventing oxidative stress-indu-ced apoptosis of H9C2 cells. J Ginseng Res 44(2):258–266. https://doi.org/10.1016/j.jgr.2018.12.004

Article  PubMed  Google Scholar 

Feng D, Wang B, Wang L et al (2017) Pre-ischemia melatonin treatment alleviated acute neuronal injury after ischemic stroke by inhibiting endoplasmic reticulum stress-dependent autophagy via PERK and IRE1 signalings. J Pineal Res 62(3). https://doi.org/10.1111/jpi.12395

Guan QH, Pei DS, Zhang QG et al (2005) The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways. Brain Res 1035(1):51–59. https://doi.org/10.1016/j.brainres.2004.11.050

Article  CAS  PubMed  Google Scholar 

Guo M-m, Qu S-b, Lu H-l et al (2021) Biochanin A alleviates cerebral ische-mia/reperfusion injury by Suppressing endoplasmic reticulum stress-induced apoptosis and p38MAPK signaling pathway in vivo and in vitro. Front Endocrinol 12. https://doi.org/10.3389/fendo.2021.646720

He R, Jiang Y, Shi Y et al (2020) Curcumin-laden exosomes target ischemic brain tissue and alleviate cerebral ischemia-reperfusion injury by inhibiting ROS-mediated mitochondrial apoptosis. Mater Sci Eng C Mater Biol Appl 117:111314. https://doi.org/10.1016/j.msec.2020.111314

Article  CAS  PubMed  Google Scholar 

Hongyun H, Tao G, Pengyue Z et al (2017) Puerarin provides a neuroprotection against transient cerebral ischemia by attenuating autophagy at the ischemic penumbra in neurons but not in astrocytes. Neuroscience Letters 643:45–51. https://doi.org/10.1016/j.neulet.2017.02.009

Article  CAS  PubMed  Google Scholar 

Hui Z, Wang S, Li J et al (2022) Compound Tongluo Decoction inhibits endoplasmic reticulum stress-induced ferroptosis and promoted angiogenesis by activating the Sonic Hedgehog pathway in cerebral infarction. J Ethnopharmacol 283. https://doi.org/10.1016/j.jep.2021.114634

Ji M, Niu S, Guo J et al (2020) Silencing RNF13 alleviates Parkinson’s disease - like problems in mouse models by regulating the endoplasmic reticulum stress-mediated IRE1α-TRAF2-ASK1-JNK pathway. J Mol Neurosci 70(12):1977–1986. https://doi.org/10.1007/s12031-020-01599-4

Article  CAS  PubMed  Google Scholar 

Li CY, Yang P, Jiang YL et al (2020) Ginsenoside Rb1 attenuates cardiomyocyte apoptosis induced by myocardial ischemia reperfusion injury through m-TOR signal pathway. Biomed Pharmacother 125:109913. https://doi.org/10.1016/j.biopha.2020.109913

Article  CAS  PubMed  Google Scholar 

Li Y, Xu Q-q, Shan C-s et al (2018) Combined use of emodin and ginsenoside Rb1 exerts synergistic neuroprotection in cerebral ischemia/reperfusion rats. Front Pharmacol 9. https://doi.org/10.3389/fphar.2018.00943

Li J, Zhang J, Zhang Y et al (2019) TRAF2 protects against cerebral ischemia-induced brain injury by suppressing necroptosis. Cell Death Dis 10(5). https://doi.org/10.1038/s41419-019-1558-5

Liang J, Yu Y, Wang B et al (2013) Ginsenoside Rb1 attenuates oxygen-glucose deprivation-induced apoptosis in SH-SY5Y cells via protection of mitoc-hondria and inhibition of AIF and cytochrome c release. Molecules 18(10):12777–12792. https://doi.org/10.3390/molecules181012777

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lin Y, Chen T, Hung C et al (2018) Melatonin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress International. J Mol Med. https://doi.org/10.3892/ijmm.2018.3607

Longa EZ, Weinstein PR, Carlson S et al (1989) Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20(1):84–91. https://doi.org/10.1161/01.str.20.1.84

Article  CAS  PubMed  Google Scholar 

Lu L, Ao H, Fu J et al (2023) Ginsenoside Rb1 stabilized and paclitaxel/protopanaxadiol co-loaded nanoparticles for synergistic treatment of breast tumor. Biomed Pharmacother 163:114870. https://doi.org/10.1016/j.biopha.2023.114870

Article  CAS  PubMed  Google Scholar 

Ni H, Rui Q, Li D et al (2018) The role of IRE1 signaling in the central nervous system diseases. Curr Neuropharmacol 16(9):1340–1347. https://doi.org/10.2174/1570159x16666180416094646

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pan XW, Wang MJ, Gong SS et al (2020) YiQiFuMai lyophilized injection ameliorates tPA-induced hemorrhagic transformation by inhibiting cytoskeletal rearrangement associated with ROCK1 and NF-κB signaling pathways. J Ethnopharmacol 262:113161. https://doi.org/10.1016/j.jep.2020.113161

Article  CAS  PubMed  Google Scholar 

Pan B, Sun J, Liu Z et al (2021) Longxuetongluo capsule protects against cerebral ischemia/reperfusion injury through endoplasmic reticulum stress and MAPK-mediated mechanisms. J Adv Res 33:215–225. https://doi.org/10.1016/j.jare.2021.01.016

Article  CAS  PubMed  PubMed Central  Google Scholar 

Park H, Seol GH, Ryu S et al (2016) Neuroprotective effects of (-)-linalool against oxygen-glucose deprivation-induced neuronal injury. Arch Pharm Res 39(4):555–564. https://doi.org/10.1007/s12272-016-0714-z

Article  CAS  PubMed  Google Scholar 

Stanzione F, Giangreco I, Cole JC (2021) Use of molecular docking computational tools in drug discovery. Prog Med Chem 60:273–343. https://doi.org/10.1016/bs.pmch.2021.01.004

Article  PubMed  Google Scholar 

Su XT, Wang L, Ma SM et al (2020) Mechanisms of acupuncture in the regulation of oxidative stress in treating ischemic stroke. Oxid Med Cell Longev 2020:7875396. https://doi.org/10.1155/2020/7875396

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tabas I, Ron D (2011) Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat Cell Biol 13(3):184–190. https://doi.org/10.1038/ncb0311-184

Article  CAS  PubMed  PubMed Central  Google Scholar 

Taguchi Yuki, Imaoka Koichi, Kataoka Michiyo et al (2015) Yip1A, a novel host factor for the activation of the IRE1 pathway of the unfolded protein response during Brucella infection. PLoS pathogens 11(3):e1004747. https://doi.org/10.1371/journal.ppat.1004747

Article  CAS  PubMed  PubMed Central 

留言 (0)

沒有登入
gif