Tulving, E. in Organization of Memory (eds Tulving, E. & Donaldson, W.) 382–403 (Academic Press, 1972).

Squire, L. R. Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. Psychol. Rev. 99, 195–231 (1992).

Article  CAS  PubMed  Google Scholar 

Eichenbaum, H. & Cohen, N. J. Can we reconcile the declarative memory and spatial navigation views on hippocampal function? Neuron 83, 764–770 (2014).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Frankland, P. W. & Bontempi, B. The organization of recent and remote memories. Nat. Rev. Neurosci. 6, 119–130 (2005).

Article  CAS  PubMed  Google Scholar 

Dragoi, G. & Tonegawa, S. Preplay of future place cell sequences by hippocampal cellular assemblies. Nature 469, 397–401 (2011).

Article  CAS  PubMed  Google Scholar 

Dragoi, G. & Tonegawa, S. Selection of preconfigured cell assemblies for representation of novel spatial experiences. Phil. Trans. R. Soc. Lond. B 369, 20120522 (2014).

Article  Google Scholar 

Liu, K., Sibille, J. & Dragoi, G. Preconfigured patterns are the primary driver of offline multi-neuronal sequence replay. Hippocampus 29, 275–283 (2019).

Article  PubMed  Google Scholar 

Dragoi, G. Internal operations in the hippocampus: single cell and ensemble temporal coding. Front. Syst. Neurosci. 7, 46 (2013).

Article  PubMed  PubMed Central  Google Scholar 

Monaco, J. D., Rao, G., Roth, E. D. & Knierim, J. J. Attentive scanning behavior drives one-trial potentiation of hippocampal place fields. Nat. Neurosci. 17, 725–731 (2014).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dragoi, G. & Tonegawa, S. Distinct preplay of multiple novel spatial experiences in the rat. Proc. Natl Acad. Sci. USA 110, 9100–9105 (2013).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Grosmark, A. D. & Buzsáki, G. Diversity in neural firing dynamics supports both rigid and learned hippocampal sequences. Science 351, 1440–1443 (2016).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Olafsdóttir, H. F., Barry, C., Saleem, A. B., Hassabis, D. & Spiers, H. J. Hippocampal place cells construct reward related sequences through unexplored space. eLife 4, e06063 (2015).

Article  PubMed  PubMed Central  Google Scholar 

Liu, Y., Dolan, R. J., Kurth-Nelson, Z. & Behrens, T. E. J. Human replay spontaneously reorganizes experience. Cell 178, 640–652 (2019).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vaz, A. P., Wittig, J. H. Jr., Inati, S. K. & Zaghloul, K. A. Backbone spiking sequence as a basis for preplay, replay, and default states in human cortex. Nat. Commun. 14, 4723 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu, K., Sibille, J. & Dragoi, G. Orientation selectivity enhances context generalization and generative predictive coding in the hippocampus. Neuron 109, 3688–3698 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dragoi, G. Cell assemblies, sequences and temporal coding in the hippocampus. Curr. Opin. Neurobiol. 64, 111–118 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Buzsaki, G. Two-stage model of memory trace formation: a role for ‘noisy’ brain states. Neuroscience 31, 551–570 (1989).

Article  CAS  PubMed  Google Scholar 

Girardeau, G., Benchenane, K., Wiener, S. I., Buzsaki, G. & Zugaro, M. B. Selective suppression of hippocampal ripples impairs spatial memory. Nat. Neurosci. 12, 1222–1223 (2009).

Article  CAS  PubMed  Google Scholar 

Ego-Stengel, V. & Wilson, M. A. Disruption of ripple-associated hippocampal activity during rest impairs spatial learning in the rat. Hippocampus 20, 1–10 (2010).

Article  PubMed  PubMed Central  Google Scholar 

Gridchyn, I., Schoenenberger, P., O’Neill, J. & Csicsvari, J. Assembly-specific disruption of hippocampal replay leads to selective memory deficit. Neuron 106, 291–300 (2020).

Article  CAS  PubMed  Google Scholar 

Lee, A. K. & Wilson, M. A. Memory of sequential experience in the hippocampus during slow wave sleep. Neuron 36, 1183–1194 (2002).

Article  CAS  PubMed  Google Scholar 

Davidson, T. J., Kloosterman, F. & Wilson, M. A. Hippocampal replay of extended experience. Neuron 63, 497–507 (2009).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Farooq, U., Sibille, J., Liu, K. & Dragoi, G. Strengthened temporal coordination within pre-existing sequential cell assemblies supports trajectory replay. Neuron 103, 719–733 (2019).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Drieu, C., Todorova, R. & Zugaro, M. Nested sequences of hippocampal assemblies during behavior support subsequent sleep replay. Science 362, 675–679 (2018).

Article  CAS  PubMed  Google Scholar 

Farooq, U. & Dragoi, G. Emergence of preconfigured and plastic time-compressed sequences in early postnatal development. Science 363, 168–173 (2019).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Muessig, L., Lasek, M., Varsavsky, I., Cacucci, F. & Wills, T. J. Coordinated emergence of hippocampal replay and theta sequences during post-natal development. Curr. Biol. 29, 834–840(2019).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dragoi, G. The generative grammar of the brain: a critique of internally generated representations. Nat. Rev. Neurosci. 25, 60–75 (2024).

Article  CAS  PubMed  Google Scholar 

Farooq, U. & Dragoi, G. Geometric experience sculpts the development and dynamics of hippocampal sequential cell assemblies. Preprint at bioRxiv https://doi.org/10.1101/2023.12.04.570026 (2023).

Travaglia, A., Bisaz, R., Sweet, E. S., Blitzer, R. D. & Alberini, C. M. Infantile amnesia reflects a developmental critical period for hippocampal learning. Nat. Neurosci. 19, 1225–1233 (2016).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bessieres, B., Travaglia, A., Mowery, T. M., Zhang, X. & Alberini, C. M. Early life experiences selectively mature learning and memory abilities. Nat. Commun. 11, 628 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ramsaran, A. I. et al. A shift in the mechanisms controlling hippocampal engram formation during brain maturation. Science 380, 543–551 (2023).

Article  CAS  PubMed  Google Scholar 

Donato, F. et al. The ontogeny of hippocampus-dependent memories. J. Neurosci. 41, 920–926 (2021).