Advanced age and neurological recovery in elderly patients with out-of-hospital cardiac arrest treated with targeted temperature management: a nationwide population‑based registry study 2016–2020

Korea Disease Control and Prevention Agency. Cardiac Arrest Surveillance. Available from: https://www.kdca.go.kr/injury/biz/injury/bsnsIntrcn/acfdsesCaExaminMain.do

Bernard SA, Gray TW, Buist MD, Jones BM, Silvester W, Gutteridge G et al (2002) Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 346(8):557–563

Article  PubMed  Google Scholar 

Group HaCAS (2002) Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 346(8):549–556

Article  Google Scholar 

Nielsen N, Hovdenes J, Nilsson F, Rubertsson S, Stammet P, Sunde K et al (2009) Outcome, timing and adverse events in therapeutic hypothermia after out-of-hospital cardiac arrest. Acta Anaesthesiol Scand 53(7):926–934

Article  CAS  PubMed  Google Scholar 

Dankiewicz J, Cronberg T, Lilja G, Jakobsen JC, Levin H, Ullén S et al (2021) Hypothermia versus normothermia after out-of-hospital cardiac arrest. N Engl J Med 384(24):2283–2294

Article  PubMed  Google Scholar 

Polderman KH (2009) Mechanisms of action, physiological effects, and complications of hypothermia. Crit Care Med 37(7):S186–S202

Article  PubMed  Google Scholar 

Baumann E, Preston E, Slinn J, Stanimirovic D (2009) Post-ischemic hypothermia attenuates loss of the vascular basement membrane proteins, agrin and SPARC, and the blood–brain barrier disruption after global cerebral ischemia. Brain Res 1269:185–197

Article  CAS  PubMed  Google Scholar 

Gong P, Hua R, Zhang Y, Zhao H, Tang Z, Mei X et al (2013) Hypothermia-induced neuroprotection is associated with reduced mitochondrial membrane permeability in a swine model of cardiac arrest. J Cereb Blood Flow Metab 33(6):928–934

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tahsili-Fahadan P, Farrokh S, Geocadin RG (2018) Hypothermia and brain inflammation after cardiac arrest. Brain Circ 4(1):1

Article  PubMed  PubMed Central  Google Scholar 

Arrich J, Herkner H, Müllner D, Behringer W (2021) Targeted temperature management after cardiac arrest. A systematic review and meta-analysis of animal studies. Resuscitation 162:47–55

Article  PubMed  Google Scholar 

Cabeza R (2002) Hemispheric asymmetry reduction in older adults: the HAROLD model. Psychol Aging 17(1):85

Article  PubMed  Google Scholar 

Vidal-Piñeiro D, Valls-Pedret C, Fernández-Cabello S, Arenaza-Urquijo EM, Sala-Llonch R, Solana E et al (2014) Decreased default mode network connectivity correlates with age-associated structural and cognitive changes. Front Aging Neurosci 6:256

PubMed  PubMed Central  Google Scholar 

Christian KM, Song H, Ming G-L (2014) Functions and dysfunctions of adult hippocampal neurogenesis. Annu Rev Neurosci 37:243–262

Article  CAS  PubMed  PubMed Central  Google Scholar 

Damoiseaux JS, Beckmann C, Arigita ES, Barkhof F, Scheltens P, Stam C et al (2008) Reduced resting-state brain activity in the “default network” in normal aging. Cereb Cortex 18(8):1856–1864

Article  CAS  PubMed  Google Scholar 

Wallmüller C, Testori C, Sterz F, Stratil P, Schober A, Herkner H et al (2016) Limited effect of mild therapeutic hypothermia on outcome after prolonged resuscitation. Resuscitation 98:15–19

Article  PubMed  Google Scholar 

Testori C, Sterz F, Holzer M, Losert H, Arrich J, Herkner H et al (2012) The beneficial effect of mild therapeutic hypothermia depends on the time of complete circulatory standstill in patients with cardiac arrest. Resuscitation 83(5):596–601

Article  PubMed  Google Scholar 

Libungan B, Lindqvist J, Strömsöe A, Nordberg P, Hollenberg J, Albertsson P et al (2015) Out-of-hospital cardiac arrest in the elderly: a large-scale population-based study. Resuscitation 94:28–32

Article  PubMed  Google Scholar 

Oh SJ, Kim JJ, Jang JH, Hwang IC, Woo JH, Lim YS et al (2018) Age is related to neurological outcome in patients with out-of-hospital cardiac arrest (OHCA) receiving therapeutic hypothermia (TH). Am J Emerg Med 36(2):243–247

Article  PubMed  Google Scholar 

Nakamura F, Kajino K, Kitamura T, Daya MR, Ong ME, Matsuyama T et al (2019) Impact of age on survival of patients with out-of-hospital cardiac arrest transported to tertiary emergency medical institutions in Osaka, Japan. Geriatrics Gerontol Int 19(11):1088–1095

Article  Google Scholar 

Nakajima S, Matsuyama T, Okada N, Kandori K, Okada A, Okada Y et al (2023) Targeted temperature management on outcome of older adult patients after out-of-hospital cardiac arrest. Am J Emerg Med 66:61–66

Article  PubMed  Google Scholar 

Park G, Ahn C, Kim JH (2022) Nationwide population-based study of poisoning-induced out-of-hospital cardiac arrest in South Korea. BMJ Open 12(4):e060378

Article  PubMed  PubMed Central  Google Scholar 

Jang Y, Kim TH, Lee SY, Ro YS, Hong KJ, Song KJ et al (2022) Association of transport time interval with neurologic outcome in out-of-hospital cardiac arrest patients without return of spontaneous circulation on scene and the interaction effect according to prehospital airway management. Clin Exp Emerg Med 9(2):93

Article  PubMed  PubMed Central  Google Scholar 

National Fire Agency. Organization of the National fire agency [Available from: https://www.nfa.go.kr/eng/agency/organization/organization/

Jacobs I, Nadkarni V, Arrest ITFoC, Outcomes CR, Participants C, Bahr J, et al (2004) Cardiac arrest and cardiopulmonary resuscitation outcome reports: update and simplification of the Utstein templates for resuscitation registries: a statement for healthcare professionals from a task force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian Resuscitation Council, New Zealand Resuscitation Council, Heart and Stroke Foundation of Canada, Inter American Heart Foundation, Resuscitation Councils of Southern Africa). Circulation 110(21):3385–97

Daya MR, Schmicker RH, Zive DM, Rea TD, Nichol G, Buick JE et al (2015) Out-of-hospital cardiac arrest survival improving over time: results from the Resuscitation Outcomes Consortium (ROC). Resuscitation 91:108–115

Article  PubMed  PubMed Central  Google Scholar 

Panchal AR, Bartos JA, Cabañas JG, Donnino MW, Drennan IR, Hirsch KG et al (2020) Part 3: adult basic and advanced life support: 2020 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation 142(16_Suppl_2):S366–S468

Article  PubMed  Google Scholar 

Nolan JP, Sandroni C, Böttiger BW, Cariou A, Cronberg T, Friberg H et al (2021) European resuscitation council and European society of intensive care medicine guidelines 2021: post-resuscitation care. Resuscitation 161:220–269

Article  PubMed  Google Scholar 

Ivacko JA, Sun R, Silverstein FS (1996) Hypoxic-ischemic brain injury induces an acute microglial reaction in perinatal rats. Pediatr Res 39(1):39–47

Article  CAS  PubMed  Google Scholar 

Kumar K, Evans AT (1997) Effect of hypothermia on microglial reaction in ischemic brain. NeuroReport 8(4):947–950

Article  CAS  PubMed  Google Scholar 

Kumar A, Stoica BA, Sabirzhanov B, Burns MP, Faden AI, Loane DJ (2013) Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states. Neurobiol Aging 34(5):1397–1411

Article  CAS  PubMed  Google Scholar 

Dumas F, Grimaldi D, Zuber B, Fichet J, Charpentier J, Pène F et al (2011) Is hypothermia after cardiac arrest effective in both shockable and nonshockable patients? Insights from a large registry. Circulation 123(8):877–886

Article  PubMed  Google Scholar 

留言 (0)

沒有登入
gif