Jensen, S. B. K. et al. Healthy weight loss maintenance with exercise, GLP-1 receptor agonist, or both combined followed by one year without treatment: a post-treatment analysis of a randomised placebo-controlled trial. EClinicalMedicine 69, 102475 (2024).

Article  PubMed  PubMed Central  Google Scholar 

Ansari, S., Khoo, B. & Tan, T. Targeting the incretin system in obesity and type 2 diabetes mellitus. Nat. Rev. Endocrinol. https://doi.org/10.1038/s41574-024-00979-9 (2024).

Article  PubMed  Google Scholar 

Jastreboff, A. M. et al. Triple–hormone-receptor agonist retatrutide for obesity — a phase 2 trial. New Eng. J. Med. 389, 514–526 (2023).

Article  CAS  PubMed  Google Scholar 

Jensen, S. B. K. et al. Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function. Obesity 31, 977–989 (2023).

Article  CAS  PubMed  Google Scholar 

Lincoff, A. M. et al. Semaglutide and cardiovascular outcomes in obesity without diabetes. New Eng. J. of Med. 389, 2221–2232 (2023).

Article  CAS  Google Scholar 

García-Vega, D. et al. Semaglutide modulates prothrombotic and atherosclerotic mechanisms, associated with epicardial fat, neutrophils and endothelial cells network. Cardiovasc. Diabetol. 23, 1 (2024).

Article  PubMed  PubMed Central  Google Scholar 

Ashcroft, S. P., Stocks, B., Egan, B. & Zierath, J. R. Exercise induces tissue-specific adaptations to enhance cardiometabolic health. Cell Metab. 36, 278–300 (2024).

Article  CAS  PubMed  Google Scholar 

Corbin, K. D. et al. Glucagon-like peptide-1/glucagon receptor agonism associates with reduced metabolic adaptation and higher fat oxidation: A randomized trial. Obesity 31, 350–362 (2023).

Article  CAS  PubMed  Google Scholar 

Melson, E., Ashraf, U., Papamargaritis, D. & Davies, M. J. What is the pipeline for future medications for obesity? Int. J. Obes. https://doi.org/10.1038/s41366-024-01473-y (2024).

Article  Google Scholar 

Herrou, J. et al. Narrative review of effects of glucagon-like peptide-1 receptor agonists on bone health in people living with obesity. Calcif. Tissue Int. 114, 86–97 (2024).

Article  CAS  PubMed  Google Scholar