A targeted gene panel illuminates pathogenesis in young people with unexplained kidney failure

ASW acknowledges support from the MRC/UKRI project MR/Y008340/1. MS acknowledges support from Nephrotic Syndrome Trust and MRC precision medicine grant MR/R013942/1.

The UK Gene Panel Study Group: Charlotte Bebb—Nephrology, Nottingham University Hospitals NHS Trust, Nottingham, UK. Fiona Beecroft—Genetics, Birmingham Women's and Children’s NHS Foundation Trust, Birmingham UK. Emma Burkitt—Genetics, Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust and University of Manchester, Manchester, UK. Deirdre Cilliers—Oxford Centre for Genomic Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Abhijit Dixit—Clinical Genetics, City Hospital Campus, Nottingham University Hospitals NHS Trust, Nottingham, UK. Jack Galliford—Nephrology, North Bristol NHS Trust, Bristol, UK. Wesley Hayes—Paediatric Nephrology, Great Ormond Street Hospital, London, UK. Katherine A. Hillman—Nephrology, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. Richard Holt—Paediatric Nephrology, Alder Hey Children’s Hospital, Liverpool, UK. Joanna Jarvis—Genetics, Birmingham Women's and Children’s NHS Foundation Trust, Birmingham, UK. Caroline Jones—Paediatric Nephrology, Alder Hey Children's Hospital, Liverpool, UK. Arveen Kamath—Institute of Medical Genetics, All Wales Medical Genetics Service, University Hospital of Wales, Cardiff, UK. Mira Kharbanda—Genetics, University Hospital Southampton NHS Foundation Trust, Southampton, UK. Alison Kraus—Genetics, Leeds Teaching University Hospital NHS Foundation Trust, Leeds, UK. Rajesh Krishnan—Paediatric Nephrology, University Hospital of Wales, Cardiff, UK. Harry Leitch— Department of Clinical Genetics, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK Kay Metcalfe—Genetics, Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. Mordi Muorah—Paediatric Nephrology, Birmingham Children’s Hospital, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, UK. Nicholas Plant—Paediatric Nephrology,Royal Manchester Children’s Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. Mohan Shenoy—Paediatric Nephrology, Royal Manchester Children’s Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. Helen M. Stuart—Genetics, Manchester Centre for Genetic Medicine, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. Judith Van Der Voort—Paediatric Nephrology, Cardiff and Vale University Health Board, Cardiff, UK. Emma Wakeling—Genetics, North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK. Denise Williams—Genetics, Birmingham Women's and Children’s NHS Foundation Trust, Birmingham, UK.

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