Vahanian A, Beyersdorf F, Praz F, Milojevic M, Baldus S, Bauersachs J, Capodanno D, Conradi L, De Bonis M, De Paulis R, Delgado V, Freemantle N, Gilard M, Haugaa KH, Jeppsson A, Jüni P, Pierard L, Prendergast BD, Sádaba JR, Tribouilloy C, Wojakowski W, Neumann F-J, Myers P, Abdelhamid M, Achenbach S, Asteggiano R, Barili F, Borger MA, Carrel T, Collet J-P, Foldager D, Habib G, Hassager C, Irs A, Iung B, Jahangiri M, Katus HA, Koskinas KC, Massberg S, Mueller CE, Nielsen JC, Pibarot P, Rakisheva A, Roffi M, Rubboli A, Shlyakhto E, Siepe M, Sitges M, Sondergaard L, Sousa-Uva M, Tarantini G, Zamorano JL, Praz F, Milojevic M, Baldus S, Bauersachs J, Capodanno D, Conradi L, De Bonis M, De Paulis R, Delgado V, Freemantle N, Gilard M, Haugaa KH, Jeppsson A, Jüni P, Pierard L, Prendergast BD, Sádaba JR, Tribouilloy C, Wojakowski W (2021) 2021 ESC/EACTS guidelines for the management of valvular heart disease. Eur Heart J 43(7):561–632. https://doi.org/10.1093/eurheartj/ehab395

Article  Google Scholar 

Otto CM, Nishimura RA, Bonow RO, Carabello BA, Erwin JP 3rd, Gentile F, Jneid H, Krieger EV, Mack M, McLeod C, O’Gara PT, Rigolin VH, Sundt TM 3rd, Thompson A, Toly C (2021) 2020 ACC/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation 143(5):e72–e227. https://doi.org/10.1161/CIR.0000000000000923

Article  PubMed  Google Scholar 

Steffen J, Reissig N, Andreae D, Beckmann M, Haum M, Fischer J, Theiss H, Braun D, Orban M, Rizas K, Sadoni S, Nabauer M, Peterss S, Hausleiter J, Massberg S, Deseive S (2022) TAVI in patients with low-flow low-gradient aortic stenosis-short-term and long-term outcomes. Clin Res Cardiol. https://doi.org/10.1007/s00392-022-02011-4

Article  PubMed  PubMed Central  Google Scholar 

Genereux P, Pibarot P, Redfors B, Mack MJ, Makkar RR, Jaber WA, Svensson LG, Kapadia S, Tuzcu EM, Thourani VH, Babaliaros V, Herrmann HC, Szeto WY, Cohen DJ, Lindman BR, McAndrew T, Alu MC, Douglas PS, Hahn RT, Kodali SK, Smith CR, Miller DC, Webb JG, Leon MB (2017) Staging classification of aortic stenosis based on the extent of cardiac damage. Eur Heart J 38(45):3351–3358. https://doi.org/10.1093/eurheartj/ehx381

Article  PubMed  PubMed Central  Google Scholar 

Deseive S, Steffen J, Beckmann M, Jochheim D, Orban M, Zadrozny M, Gschwendtner S, Braun D, Rizas K, Curta A, Hagl C, Theiss HD, Mehilli J, Massberg S, Hausleiter J (2020) CT-determined tricuspid annular dilatation is associated with increased 2-year mortality in TAVR patients. JACC Cardiovasc Interv 13(21):2497–2507. https://doi.org/10.1016/j.jcin.2020.06.027

Article  PubMed  Google Scholar 

Ren B, Spitzer E, Geleijnse ML, Zijlstra F, de Jaegere PPT, Van Mieghem NM, Tijssen JG (2018) Right ventricular systolic function in patients undergoing transcatheter aortic valve implantation: a systematic review and meta-analysis. Int J Cardiol 257:40–45. https://doi.org/10.1016/j.ijcard.2018.01.117

Article  PubMed  Google Scholar 

Leurent G, Auffret V, Donal E (2022) Right ventricular-pulmonary artery coupling: a simple marker to guide complex clinical decisions? JACC Cardiovasc Interv 15(18):1834–1836. https://doi.org/10.1016/j.jcin.2022.08.020

Article  PubMed  Google Scholar 

Rudski LG, Lai WW, Afilalo J, Hua L, Handschumacher MD, Chandrasekaran K, Solomon SD, Louie EK, Schiller NB (2010) Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am Soc Echocardiogr 23(7):685–713. https://doi.org/10.1016/j.echo.2010.05.010. quiz 786-688

Article  PubMed  Google Scholar 

Vanderpool RR, Pinsky MR, Naeije R, Deible C, Kosaraju V, Bunner C, Mathier MA, Lacomis J, Champion HC, Simon MA (2015) RV-pulmonary arterial coupling predicts outcome in patients referred for pulmonary hypertension. Heart 101(1):37–43. https://doi.org/10.1136/heartjnl-2014-306142

Article  PubMed  Google Scholar 

Guazzi M, Bandera F, Pelissero G, Castelvecchio S, Menicanti L, Ghio S, Temporelli PL, Arena R (2013) Tricuspid annular plane systolic excursion and pulmonary arterial systolic pressure relationship in heart failure: an index of right ventricular contractile function and prognosis. Am J Physiol Heart Circ Physiol 305(9):H1373-1381. https://doi.org/10.1152/ajpheart.00157.2013

Article  CAS  PubMed  Google Scholar 

Doldi PM, Stolz L, Kalbacher D, Koll B, Geyer M, Ludwig S, Orban M, Braun D, Weckbach LT, Stocker TJ, Nabauer M, Higuchi S, Ruf T, Da Rocha ESJ, Wild M, Tence N, Unterhuber M, Schofer N, Petrescu A, Thiele H, Lurz P, Lubos E, von Bardeleben S, Karam N, Samim D, Paradis JM, Iliadis C, Xhepa E, Hagl C, Massberg S, Hausleiter J, EuroSmr I-M (2022) Right ventricular dysfunction predicts outcome after transcatheter mitral valve repair for primary mitral valve regurgitation. Eur J Heart Fail. https://doi.org/10.1002/ejhf.2661

Article  PubMed  Google Scholar 

Stolz L, Doldi PM, Weckbach LT, Stocker TJ, Braun D, Orban M, Wild MG, Hagl C, Massberg S, Nabauer M, Hausleiter J, Orban M (2022) Right ventricular function in transcatheter mitral and tricuspid valve edge-to-edge repair. Front Cardiovasc Med 9:993618. https://doi.org/10.3389/fcvm.2022.993618

Article  PubMed  PubMed Central  Google Scholar 

Stolz L, Weckbach LT, Karam N, Kalbacher D, Praz F, Lurz P, Omran H, Iliadis C, Hausleiter J, Euro TRI (2023) Invasive right ventricular to pulmonary artery coupling in patients undergoing transcatheter edge-to-edge tricuspid valve repair. JACC Cardiovasc Imaging 16(4):564–566. https://doi.org/10.1016/j.jcmg.2022.10.004

Article  PubMed  Google Scholar 

Pibarot P, Iung B, Cavalcante JL (2019) Risk stratification in patients with aortic stenosis: pay more attention to the right-side unit! JACC Cardiovasc Interv 12(21):2169–2172. https://doi.org/10.1016/j.jcin.2019.08.029

Article  PubMed  Google Scholar 

Vizzardi E, Gavazzoni M, Sciatti E, Dallapellegrina L, Bernardi N, Raddino R, Fiorina C, Adamo M, Metra M (2020) Right ventricular deformation and right ventricular-arterial coupling in patients with heart failure due to severe aortic stenosis undergoing TAVI: long-term results. Am J Cardiovasc Dis 10(3):150–163

PubMed  PubMed Central  Google Scholar 

Baumgartner HC, Hung JC-C, Bermejo J, Chambers JB, Edvardsen T, Goldstein S, Lancellotti P, LeFevre M, Miller F Jr, Otto CM (2017) Recommendations on the echocardiographic assessment of aortic valve stenosis: a focused update from the European Association of Cardiovascular Imaging and the American Society of Echocardiography. Eur Heart J Cardiovasc Imaging 18(3):254–275. https://doi.org/10.1093/ehjci/jew335

Article  PubMed  Google Scholar 

Qureshi MY, Eidem BW, Reece CL, O’Leary PW (2015) Two-dimensional measurement of tricuspid annular plane systolic excursion in children: can it substitute for an m-mode assessment? Echocardiography 32(3):528–534. https://doi.org/10.1111/echo.12687

Article  PubMed  Google Scholar 

Lillo R, Graziani F, Ingrasciotta G, Przbybylek B, Iannaccone G, Locorotondo G, Pedicino D, Aurigemma C, Romagnoli E, Trani C, Lanza GA, Lombardo A, Burzotta F, Massetti M (2022) Right ventricle systolic function and right ventricle-pulmonary artery coupling in patients with severe aortic stenosis and the early impact of TAVI. Int J Cardiovasc Imaging. https://doi.org/10.1007/s10554-022-02569-0

Article  PubMed  Google Scholar 

Généreux P, Piazza N, Alu MC, Nazif T, Hahn RT, Pibarot P, Bax JJ, Leipsic JA, Blanke P, Blackstone EH, Finn MT, Kapadia S, Linke A, Mack MJ, Makkar R, Mehran R, Popma JJ, Reardon M, Rodes-Cabau J, Van Mieghem NM, Webb JG, Cohen DJ, Leon MB (2021) Valve Academic Research Consortium 3: updated endpoint definitions for aortic valve clinical research. Eur Heart J 42(19):1825–1857. https://doi.org/10.1093/eurheartj/ehaa799

Article  PubMed  Google Scholar 

Scrucca L, Santucci A, Aversa F (2010) Regression modeling of competing risk using R: an in depth guide for clinicians. Bone Marrow Transplant 45(9):1388–1395. https://doi.org/10.1038/bmt.2009.359

Article  CAS  PubMed  Google Scholar 

Cahill TJ, Pibarot P, Yu X, Babaliaros V, Blanke P, Clavel MA, Douglas PS, Khalique OK, Leipsic J, Makkar R, Alu MC, Kodali S, Mack MJ, Leon MB, Hahn RT (2022) Impact of right ventricle-pulmonary artery coupling on clinical outcomes in the PARTNER 3 Trial. JACC Cardiovasc Interv 15(18):1823–1833. https://doi.org/10.1016/j.jcin.2022.07.005

Article  PubMed  Google Scholar 

Adamo M, Maccagni G, Fiorina C, Giannini C, Angelillis M, Costa G, Trani C, Burzotta F, Bruschi G, Merlanti B, Poli A, Ferrara E, Fineschi M, Iadanza A, Chizzola G, Metra M (2022) Prognostic value of right ventricle to pulmonary artery coupling in transcatheter aortic valve implantation recipients. J Cardiovasc Med (Hagerstown) 23(9):615–622. https://doi.org/10.2459/JCM.0000000000001336

Article  PubMed  Google Scholar 

Sultan I, Cardounel A, Abdelkarim I, Kilic A, Althouse AD, Sharbaugh MS, Gupta A, Xu J, Fukui M, Simon MA, Schindler JT, Lee JS, Gleason TG, Cavalcante JL (2019) Right ventricle to pulmonary artery coupling in patients undergoing transcatheter aortic valve implantation. Heart 105(2):117–121. https://doi.org/10.1136/heartjnl-2018-313385

Article  PubMed  Google Scholar 

Asami M, Stortecky S, Praz F, Lanz J, Raber L, Franzone A, Piccolo R, Siontis GCM, Heg D, Valgimigli M, Wenaweser P, Roost E, Windecker S, Pilgrim T (2019) Prognostic value of right ventricular dysfunction on clinical outcomes after transcatheter aortic valve replacement. JACC Cardiovasc Imaging 12(4):577–587. https://doi.org/10.1016/j.jcmg.2017.12.015

Article  PubMed  Google Scholar 

Koschutnik M, Dannenberg V, Nitsche C, Dona C, Siller-Matula JM, Winter MP, Andreas M, Zafar A, Bartko PE, Beitzke D, Loewe C, Aschauer S, Anvari-Pirsch A, Goliasch G, Hengstenberg C, Kammerlander AA, Mascherbauer J (2021) Right ventricular function and outcome in patients undergoing transcatheter aortic valve replacement. Eur Heart J Cardiovasc Imaging 22(11):1295–1303. https://doi.org/10.1093/ehjci/jeaa342

Article  PubMed  Google Scholar 

Kammerlander AA, Marzluf BA, Graf A, Bachmann A, Kocher A, Bonderman D, Mascherbauer J (2014) Right ventricular dysfunction, but not tricuspid regurgitation, is associated with outcome late after left heart valve procedure. J Am Coll Cardiol 64(24):2633–2642. https://doi.org/10.1016/j.jacc.2014.09.062

Article  PubMed  Google Scholar 

Schwartz LA, Rozenbaum Z, Ghantous E, Kramarz J, Biner S, Ghermezi M, Shimiaie J, Finkelstein A, Banai S, Aviram G, Ingbir M, Keren G, Topilsky Y (2017) Impact of right ventricular dysfunction and tricuspid regurgitation on outcomes in patients undergoing transcatheter aortic valve replacement. J Am Soc Echocardiogr 30(1):36–46. https://doi.org/10.1016/j.echo.2016.08.016

Article  PubMed  Google Scholar 

Eleid MF, Padang R, Pislaru SV, Greason KL, Crestanello J, Nkomo VT, Pellikka PA, Jentzer JC, Gulati R, Sandhu GS, Holmes DR Jr, Nishimura RA, Rihal CS, Borlaug BA (2019) Effect of transcatheter aortic valve replacement on right ventricular-pulmonary artery coupling. JACC Cardiovasc Interv 12(21):2145–2154. https://doi.org/10.1016/j.jcin.2019.07.025

Article  PubMed  Google Scholar 

Alwan L, Tomii D, Heg D, Okuno T, Lanz J, Praz F, Chong-Nguyen C, Stortecky S, Reineke D, Windecker S, Pilgrim T (2023) Impact of right ventricular-pulmonary arterial coupling on clinical outcomes in patients undergoing transcatheter aortic valve implantation. Cardiovasc Revasc Med 56:27–34. https://doi.org/10.1016/j.carrev.2023.05.008

Article  PubMed  Google Scholar 

Meucci MC, Malara S, Butcher SC, Hirasawa K, van der Kley F